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1

ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells

Kline, M P, Rajkumar, S V, Timm, M M, Kimlinger, T K, Haug, J L, Lust, J A, Greipp, P R, Kumar, S

Journal:

Year:

2007

Language:

english

File:

PDF, 646 KB

english, 2007

2

TG101209, a novel JAK2 inhibitor, has significant in vitro activity in multiple myeloma and displays preferential cytotoxicity for CD45+ myeloma cells

Vijay Ramakrishnan, Teresa Kimlinger, Jessica Haug, Michael Timm, Linda Wellik, Timothy Halling, Animesh Pardanani, Ayalew Tefferi, Sundararasan Vincent Rajkumar, Shaji Kumar

Journal:

American Journal of Hematology

Year:

2010

Language:

english

File:

PDF, 2.77 MB

english, 2010

3

Sorafenib, a multikinase inhibitor, is effective in vitro against non-hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin

Vijay Ramakrishnan, Michael Timm, Jessica L. Haug, Teresa K. Kimlinger, Timothy Halling, Linda E. Wellik, Thomas E. Witzig, S. Vincent Rajkumar, Alex A. Adjei, Shaji Kumar

Journal:

American Journal of Hematology

Year:

2012

Language:

english

File:

PDF, 1.60 MB

english, 2012

4

Katalysierte Tandemreaktion aus Cyclisierung und Pinakol-Umlagerung von 3-Silyloxy-1,5-eninen

Stefan F. Kirsch, Jörg T. Binder, Benedikt Crone, Alexander Duschek, Timm T. Haug, Clémence Liébert, Helge Menz

Journal:

Angewandte Chemie

Year:

2007

Language:

german

File:

PDF, 128 KB

german, 2007

5

Dominoreaktionen bestehend aus Heterocyclisierung und 1,2-Verschiebung – redoxneutrale und oxidative Übergangsmetallkatalyse im Vergleich

Klaus-Daniel Umland, Adeline Palisse, Timm T. Haug, Prof. Dr. Stefan F. Kirsch

Journal:

Angewandte Chemie

Year:

2011

Language:

german

File:

PDF, 335 KB

german, 2011

6

Catalyzed Tandem Reaction of 3-Silyloxy-1,5-enynes Consisting of Cyclization and Pinacol Rearrangement

Stefan F. Kirsch, Jörg T. Binder, Benedikt Crone, Alexander Duschek, Timm T. Haug, Clémence Liébert, Helge Menz

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 127 KB

english, 2007

7

Domino Reactions Consisting of Heterocyclization and 1,2-Migration—Redox-Neutral and Oxidative Transition-Metal Catalysis

Klaus-Daniel Umland, Adeline Palisse, Timm T. Haug, Prof. Dr. Stefan F. Kirsch

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 317 KB

english, 2011

8

ChemInform Abstract: Gold-Catalyzed Reactivity of 3-Silyloxy-1,5-enynes: A Synthetic Tool for the Synthesis of Complex Structures and Its Limitations.

Helge Menz, Joerg T. Binder, Benedikt Crone, Alexander Duschek, Timm T. Haug, Stefan F. Kirsch, Philipp Klahn, Clemence Liebert

Journal:

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

9

ChemInform Abstract: Reactivity of 3-Silyloxy-1,4-enynes: Gold(III)-Catalyzed Regioselective Nucleophilic Substitution.

Timm T. Haug, Tobias Harschneck, Alexander Duschek, Chang-Uk Lee, Joerg T. Binder, Helge Menz, Stefan F. Kirsch

Journal:

Year:

2009

File:

PDF, 52 KB

2009

10

ChemInform Abstract: Synthesis and Chemistry of 3(2H)-Furanones

Timm T. Haug, Stefan F. Kirsch

Journal:

Year:

2010

File:

PDF, 14 KB

2010

11

ChemInform Abstract: Domino Reactions Consisting of Heterocyclization and 1,2-Migration—Redox-Neutral and Oxidative Transition-Metal Catalysis.

Klaus-Daniel Umland, Adeline Palisse, Timm T. Haug, Stefan F. Kirsch

Journal:

Year:

2012

File:

PDF, 16 KB

2012

12

Reactivity of 3-silyloxy-1,4-enynes: Gold(III)-catalyzed regioselective nucleophilic substitution

Timm T. Haug, Tobias Harschneck, Alexander Duschek, Chang-Uk Lee, Jörg T. Binder, Helge Menz, Stefan F. Kirsch

Journal:

Journal of Organometallic Chemistry

Year:

2009

Language:

english

File:

PDF, 432 KB

english, 2009

13

Gold-catalyzed reactivity of 3-silyloxy-1,5-enynes: a synthetic tool for the synthesis of complex structures and its limitations

Helge Menz, Jörg T. Binder, Benedikt Crone, Alexander Duschek, Timm T. Haug, Stefan F. Kirsch, Philipp Klahn, Clémence Liébert

Journal:

Year:

2009

Language:

english

File:

PDF, 572 KB

english, 2009

14

Plasma levels of tumour necrosis factor alpha and interleukin-6 predict progression-free survival following thalidomide therapy in patients with previously untreated multiple myeloma

Michael A. Thompson, Thomas E. Witzig, Shaji Kumar, Michael M. Timm, Jessica Haug, Rafael Fonseca, Philip R. Greipp, John A. Lust, S. Vincent Rajkumar

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 100 KB

english, 2003

15

Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs

Ramakrishnan, V, Timm, M, Haug, J L, Kimlinger, T K, Wellik, L E, Witzig, T E, Rajkumar, S V, Adjei, A A, Kumar, S

Journal:

Year:

2009

Language:

english

File:

PDF, 1022 KB

english, 2009

16

Expression of VEGF and its receptors by myeloma cells

Kumar, S, Witzig, T E, Timm, M, Haug, J, Wellik, L, Fonseca, R, Greipp, P R, Rajkumar, S V

Journal:

Year:

2003

Language:

english

File:

PDF, 328 KB

english, 2003

17

Thymoglobulin targets multiple plasma cell antigens and has in vitro and in vivo activity in multiple myeloma

Timm, M M, Kimlinger, T K, Haug, J L, Kline, M P, Greipp, P R, Rajkumar, S V, Kumar, S K

Journal:

Year:

2006

Language:

english

File:

PDF, 269 KB

english, 2006

18

Influence of conjugation reactions on the mutagenicity of aromatic amines

Jan Hongslo, Lise Timm Haug, Peter J. Wirth, Mona Møller, Erik Dybing, Snorri S. Thorgeirsson

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1983

Language:

english

File:

PDF, 489 KB

english, 1983

19

R-(-)−gossypol (AT-101) activates programmed cell death in multiple myeloma cells

Michael P. Kline, S. Vincent Rajkumar, Michael M. Timm, Teresa K. Kimlinger, Jessica L. Haug, John A. Lust, Philip R. Greipp, Shaji Kumar

Journal:

Experimental Hematology

Year:

2008

Language:

english

File:

PDF, 475 KB

english, 2008

20

MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma

Ramakrishnan, V, Ansell, S, Haug, J, Grote, D, Kimlinger, T, Stenson, M, Timm, M, Wellik, L, Halling, T, Rajkumar, S V, Kumar, S

Journal:

Year:

2012

Language:

english

File:

PDF, 750 KB

english, 2012

21

Modulation of aromatic amine mutagenicity in Salmonella typhimurium with rat-liver 9000 g supernatant or monolayers of rat hepatocytes as an activation system

Jørn A. Holme, Lise Timm Haug, Erik Dybing

Journal:

Mutation Research/Genetic Toxicology

Year:

1983

Language:

english

File:

PDF, 753 KB

english, 1983

22

Direct Carbocyclization of Aldehydes with Alkynes: Combining Gold Catalysis with Aminocatalysis

Binder, Jörg T., Crone, Benedikt, Haug, Timm T., Menz, Helge, Kirsch, Stefan F.

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 90 KB

english, 2008

23

Total synthesis of (+)-chloriolide

Haug, Timm T., Kirsch, Stefan F.

Journal:

Organic & Biomolecular Chemistry

Year:

2010

Language:

english

File:

PDF, 115 KB

english, 2010

24

Multiple mechanisms contribute to the synergistic anti-myeloma activity of the pan-histone deacetylase inhibitor LBH589 and the rapalog RAD001

Ramakrishnan, Vijay, Kimlinger, Teresa, Timm, Michael, Haug, Jessica, Rajkumar, S. Vincent, Kumar, Shaji

Journal:

Leukemia Research

Year:

2014

Language:

english

File:

PDF, 2.50 MB

english, 2014

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